pentobarbital will lessen the level or influence of trazodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will reduce the level or result of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to the decrease in fentanyl plasma concentrations, lack of efficacy or, potentially, enhancement of the withdrawal syndrome in a affected person that has produced Bodily dependence to fentanyl.
pentobarbital will decrease the level or impact of tacrolimus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lessen the level or effect of sildenafil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Potent CYP3A4 inducers are expected to cause considerable decreases in sildenafil plasma stages
pentobarbital will decrease the extent or effect of fosphenytoin by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Watch.
pentobarbital will lower the extent or effect of tipranavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
fentanyl transdermal and pentobarbital equally raise sedation. Stay away from or Use Alternate Drug. Restrict use to sufferers for whom alternative cure alternatives are insufficient
pentobarbital will lower the extent or result of nelfinavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will minimize the level or outcome of etonogestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Therapy needs to be administered with caution, if in any respect, to individuals who are mentally depressed, have suicidal tendencies, or record of drug abuse
Warning with use for the duration of surgeries or methods in children younger than three yr or in Expecting Gals during their 3rd trimester
pentobarbital will minimize the level or outcome of eucalyptus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unidentified.
With therapeutic doses of TCAs, barbiturates raise metabolism and reduce blood concentrations of TCAs.
pentobarbital will reduce the level check here or impact of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unfamiliar.